Endocrine Abstracts

The propensity for prolactin (PRL) to form high molecular mass complexes in serum is well described. Macroprolactin (mPRL), a PRL-immunoglobulin complex (>100 kDa), is the predominant form of PRL in up to 20% of patients with hyperprolactinaemia. Big PRL (bPRL, 40–50 kDa) is a ubiquitous, minor component of serum PRL rarely the major immunoreactive form, the nature of which is unclear. Using gel filtration chromatography (GFC) we have investigated the relative abundan...

A retrospective analysis of the results of all intra-arterial calcium stimulations performed at St. Vincent’s Hospital, Dublin, in the years 2001-2006. All patients with symptoms suggestive of hypoglycemia had 72 hour fasting test with evidence of inappropriately elevated insulin and c-peptide at the time of hypoglycemia. These patients were investigated further with pancreatic imaging and selective intra-arterial calcium stimulation with hepatic venous sampling (ASVS). A...